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LILRB4 also known as CD85k and LIR-5 ILT3 is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains a 21 aa transmembrane segment and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM) LILRB4 is receptor for class I MHC antigens Recognizes a broad spectrum of HLA-A HLA-B HLA-C and HLA-G alleles
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Mesothelin also known as MSLN is a protein that in humans is encoded by the MSLN gene Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF)
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Active Motif's Nuclear Complex Co-IP Kit simplifies co-immunoprecipitation of nuclear protein complexes by providing high-quality reagents for both nuclear extract preparation and immunoprecipitation. The kit's extraction process maintains protein complexes contained in the nucleus, specifically those previously bound to DNA, while the stringency of the Co-IP reagents can be easily adjusted so you can better study protein/protein interactions of varying strength.
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EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 ?M for Rac1 in MDA-MB-435 and MDA-MB-231 cells, equally potent inhibition for Rac3. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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GenScript MonoRab sup TM /sup Anti-DYKDDDDK Magnetic Beads are super paramagnetic beads with diameter of 70 m covalently coated with a rabbit monoclonal anti-DYKDDDDK antibody The beads are supplied as 50% slurry in TBS with 50% glycerol and 0 02% sodium azide The MonoRab sup TM /sup Anti-DYKDDDDK Magnetic Beads have a binding capacity of 1 5 mg DYKDDDDK-tagged protein (Size 50KDa) per 1 ml settled beads The beads can be re-used for at least 5 times Based on our new rabbit monoclonal antibody technology (MonoRab sup TM /sup ) this beads offers high binding capacity high purity and withstand stringent washing steps especially with buffers containing high concentration of salt The beads are resistant to up to 2 M NaCl and to buffers with pH as low as 2 5
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Cell Biolabs' Lipid Quantification Kit (Fluorometric) quantifies neutral lipids in a convenient 96-well fluorescence-based microplate reader. Supernatants from plasma or serum may be tested directly after centrifugation. Lipids from cells or tissues should be extracted first before quantification. The kit includes sufficient reagents for 100 assays.
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The EasySep™ Human CD14 Positive Selection Kit II is designed to isolate highly purified CD14+ cells from fresh or previously frozen human peripheral blood mononuclear cells (PBMCs). Desired cells are targeted with Tetrameric Antibody Complexes recognizing CD14 and dextran-coated magnetic particles. Labeled cells are separated using an EasySep™ magnet without the use of columns. Cells of interest remain in the tube while unwanted cells are poured off. The CD14 antigen is strongly expressed on monocytes and macrophages and weakly on granulocytes. It is also expressed on most tissue macrophages.This product replaces the EasySep™ Human CD14 Positive Selection Kit (Catalog #18058), for even faster cell isolations and is compatible with all EasySep™ magnets.
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